Buffalo Bills coach Sean McDermott has confirmed that tight end Dalton Kincaid will not play against the San Francisco 49ers due to a knee injury, marking his second consecutive game missed. Meanwhile, linebacker Matt Milano, who has been sidelined for nearly 14 months, is listed as questionable after fully participating in practice.

The Bills, with a record of 9-2, are looking to secure their fifth straight AFC East title with a win over the 49ers. Milano's potential return could bolster the team's defense, as they prepare to activate him from injured reserve.