In 2024, the Detroit Lions' defense faced overwhelming challenges, with significant injuries impacting key players like Aidan Hutchinson and Alim McNeill throughout the season. Despite a promising start, Hutchinson's season ended early due to a leg injury, disrupting the team's pass rush and forcing the Lions to trade for Za'Darius Smith to maintain production. The defense managed to secure a top run defense ranking, but finished poorly in pass rush metrics, averaging only 2.1 sacks per game.

The linebacker unit saw promise from rookie Jack Campbell, who performed well in his first year, especially after stepping up as a play-caller due to injuries to veterans like Alex Anzalone and Derrick Barnes. The secondary struggled with consistency as Carlton Davis and Amik Robertson joined the team, but injuries limited their potential. Despite these challenges, Kerby Joseph and Brian Branch shone as a formidable safety duo, helping the defense stay competitive.