Gunnar Henderson, a standout shortstop for the Orioles, is currently sidelined with a mild intercostal strain. After a breakout season in 2024 where he hit .281 with 37 homers and a bWAR of 9.1, his health is crucial for the team's 2025 season ambitions. Henderson has never been on the injured list before, making his recovery particularly significant as the Orioles look to be competitive.

Coby Mayo has shown promise after a challenging MLB debut. With a solid track record in the minors, he has the potential to be a reliable contributor for the Orioles if he can maintain consistency.

Jackson Holliday remains a highly regarded prospect despite a rocky start to his MLB career. Expected to improve upon his disappointing rookie stats, he possesses the potential for significant contributions with projections suggesting he could tally 20 home runs and steals annually. His impressive hard-hit rate and speed metrics bolster his fantasy prospects heading into the season.

Félix Bautista is noted for his potential to emerge as a top-tier closer, showcasing skills that could lead to substantial save totals as the season progresses.

Adley Rutschman's performance has been a rollercoaster, with a strong start to the 2024 season before injuries hindered his production. He is expected to bounce back in 2025, making him a value pick in drafts.